Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1229984
rs1229984
ADH1B
0.900 GeneticVariation GWASDB In case-control analysis, ADH1B rs1229984 (H47R) showed the most significant association with the risk of AD (p = 2.63 × 10(-21), OR = 2.35). 23456092

2013
dbSNP: rs671
rs671
ALDH2
0.900 GeneticVariation GWASDB When rs671 was considered as a candidate SNP in females, it explained 23.6% of the variation in flushing response, but alcohol consumption rates were too low among females-despite familial enrichment for AD-for an adequate test of association for either AD or maximum drinks. 24277619

2014
dbSNP: rs1789891
rs1789891
ADH1B
0.820 GeneticVariation GWASDB Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. 22004471

2012
dbSNP: rs750338
rs750338
PKNOX2
C 0.810 GeneticVariation GWASDB The top hit of PKNOX2 (rs750338 with p=1.47 × 10(-6)) in the meta-analysis was replicated with the Australian Twin-Family Study of 778 families (p=1.39 × 10(-2)) Furthermore, several flanking SNPs of the top hits in the meta-analysis demonstrated borderline associations with alcohol dependence in the family sample (top SNPs were rs2269655, rs856613, and rs10496768 with p=4.58 × 10(-3), 2.1 × 10(-4), and 2.86 × 10(-3) for KIAA0040, NRD1 and THSD7B, respectively). 21703634

2011
dbSNP: rs1000579
rs1000579
STX18-AS1
0.800 GeneticVariation GWASDB Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. 22004471

2012
dbSNP: rs2835872
rs2835872
KCNJ6
G 0.800 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs4478858
rs4478858
SERINC2
G 0.800 GeneticVariation GWASDB NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. 23455491

2013
dbSNP: rs6701037
rs6701037 		C 0.800 GeneticVariation GWASDB A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs6777876
rs6777876 		G 0.800 GeneticVariation GWASDB Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample. 21314694

2011
dbSNP: rs7590720
rs7590720
MREG ; PECR
G 0.800 GeneticVariation GWASDB Genome-wide association study of alcohol dependence. 19581569

2009
dbSNP: rs896543
rs896543
LOC107986001
0.800 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013
dbSNP: rs10483038
rs10483038
KCNJ6
0.700 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs1057302
rs1057302
KIAA0040
0.700 GeneticVariation GWASDB A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. 21703634

2011
dbSNP: rs10913569
rs10913569
C1orf220
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol dependence. 20202923

2010
dbSNP: rs111372083
rs111372083
KCNJ6
0.700 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs111576572
rs111576572
KCNJ6
0.700 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs11583322
rs11583322
STK40
0.700 GeneticVariation GWASDB Dosage transmission disequilibrium test (dTDT) for linkage and association detection. 23691058

2013
dbSNP: rs11623335
rs11623335
TMEM260
0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs11922615
rs11922615
SETD5
0.700 GeneticVariation GWASDB A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. 22096494

2011
dbSNP: rs12006002
rs12006002
ADAMTSL1
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013
dbSNP: rs12392447
rs12392447
RN7SL697P
0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence. 19581569

2009
dbSNP: rs12427267
rs12427267
LOC105369901
0.700 GeneticVariation GWASDB Dosage transmission disequilibrium test (dTDT) for linkage and association detection. 23691058

2013
dbSNP: rs12482570
rs12482570
KCNJ6 ; LOC107985507
0.700 GeneticVariation GWASDB Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. 22554406

2012
dbSNP: rs12489456
rs12489456
SLC6A6
0.700 GeneticVariation GWASDB Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. 21956439

2012
dbSNP: rs12898460
rs12898460
LINC02694
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013